Removing overactive brain immune cells restored sleep in Alzheimer's mice

โฎ BeforeSleep loss in Alzheimer's was poorly explained, and its causes were unclear.
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NowResearchers have identified overactive brain immune cells as a promising target, tested so far in mice.
In short
- Overactive immune cells in the brain were found to contribute to sleep loss in Alzheimer's disease.
- Temporarily removing these cells restored more than two hours of sleep per day in mice.
- The finding points to a possible new treatment target; this work was in mice, not people.
Why the Good News Desk likes this one
Sleep loss is a common and distressing part of Alzheimer's disease. This study suggests the cause may lie in immune cells rather than only in plaques. The result comes from mice, so it is an early step toward possible treatment.
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From ScienceDaily
Scientists have uncovered an unexpected culprit behind sleep loss in Alzheimerโs disease: overactive immune cells in the brain. By temporarily removing these cells, researchers restored more than two hours of sleep per day in mice, revealing a promising new target for treatment.
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